Symbol
Name
ID

Pou4f2
POU domain, class 4, transcription factor 2
MGI:102524

Phenotype annotations related to nervous system

Darker colors indicate more annotations

Mouse Phenotypes

abnormal optic tract morphology

abnormal superior colliculus morphology

abnormal olivary pretectal nucleus morphology

abnormal suprachiasmatic nucleus morphology

abnormal lateral geniculate nucleus morphology

gliosis

abnormal innervation

abnormal sensory neuron innervation pattern

abnormal optic nerve innervation

decreased retina ganglion cell number

increased amacrine cell number

abnormal retina ganglion cell morphology

retina ganglion cell degeneration

abnormal optic nerve morphology

abnormal optic disk morphology

optic nerve degeneration

optic nerve atrophy

optic nerve hypoplasia

abnormal neuron physiology

Availability

Mouse Genotype

Pou4f2^tm1Nat/Pou4f2^tm1Nat

Pou4f2^tm1Rsd/Pou4f2^tm1Rsd

Pou4f2^tm3Whk/Pou4f2^tm3Whk

Pou4f2^tm1(ALPP)Whk/Pou4f2^tm2Whk

Pou4f2^tm4(DTA)Whk/Pou4f2^tm4(DTA)Whk
Tg(Six3-cre)69Frty/? (conditional)

Opn4^{tm1.1(cre)Saha}/Opn4⁺
Pou4f2^tm2.1Nat/Pou4f2⁺ (conditional)

Opn4^{tm1.1(cre)Saha}/Opn4⁺
Pou4f2^tm4(DTA)Whk/Pou4f2⁺
Tg(CAG-Bgeo/ALPP)1Lbe/0 (conditional)

Opn4^{tm1.1(cre)Saha}/Opn4⁺
Pou4f2^tm4(DTA)Whk/Pou4f2⁺ (conditional)

Opn4^{tm2.1(cre/ERT2)Saha}/Opn4⁺
Pou4f2^tm2.1Nat/Pou4f2⁺ (conditional)

Pou4f2^tm1Nat/Pou4f2^tm2.1Nat
Tg(Pax6-cre,GFP)2Pgr/? (conditional)

Pou4f2^tm4(DTA)Whk/Pou4f2⁺
Tg(CAG-cre/Esr1*)5Amc/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23